- +55 (31)3409-2615
- pg-biq@icb.ufmg.br
- Molecular characterization and biochemical aspects of viruses, bacteria, fungi, and protozoan parasites of human and veterinary relevance.
Associated faculty- Biochemical signaling pathways related to healthy and pathological aging
- Drug characterization for the treatment of neurodegenerative diseases.
- Structural characterization (mass spectrometry, nuclear magnetic resonance (NMR), crystallography, computational biology, and molecular modeling) and molecular docking
- Quality control of protein synthesis: mechanisms associated with synthesis and degradation of aberrant proteins encoded by defective RNAs
- Isolation, molecular characterization, synthesis and/or mechanism of action of animal toxins
- Proteomics and functional proteomics.
- Tumor cell biology for diagnostic and therapeutic purposes.
Associated faculty- Alterations in cardiac excitability in cardiomyopathies.
Associated faculty- Mechanisms of specific suppression of the immune response and their role in autoimmune disease therapy.
Associated faculty- Immunogenic, immunoregulatory, immunoprotective, and tissue damage mechanisms
- Effector molecular mechanisms of innate immunity, recognition of pathogen molecules, signal transduction, and activation phenotypes induced by pathogen molecules
- Development of computational tools for antibody studies
- Antibody repertoire characterization using big data.
- Chemokines, systemic inflammation, recruitment, and inflammation
- Immunological aspects of nutritional disorders and their role in disease onset and progression
- Inflammatory mechanisms involved in the development and maintenance of cardiovascular diseases
- Cellular and molecular mechanisms in joint injury and dysfunction (experimental rheumatology).
- Molecular mechanisms underlying host-microbiota interactions and their impacts on health and disease (parasitic diseases, Zika, dengue, chikungunya, and bacterial infections)
- Molecular and behavioral mechanisms in the development of neurodegenerative diseases and their relationship with the microbiota.
- Molecular mechanisms of neurodegenerative processes and their relationship with cognitive aspects in experimental models.
Associated faculty- Mechanism of action of natural products on cardiac excitation-contraction coupling and other pharmacological activities
- Structure-activity relationships, mechanisms of action, and biotechnological applications of proteins and peptides derived from animal venoms and secretions.
- Mucosa-associated lymphoid tissue (MALT) and its role in the induction of immunity and immune tolerance.
Associated faculty- Nano-structured formulations in vitro and in vivo
- Generation of tissues and organs through cellular and molecular engineering for application in cell therapy.
- Biochemical aspects related to nutritional alterations or disorders and the influence of nutrients on the onset, progression, and outcome of diseases.
Associated faculty- Biochemistry, molecular and cellular biology of parasites and their hosts relevant to the pathogenesis of infectious diseases.
Associated faculty- Discovery and optimization of drug candidates through molecular modeling, structural biology, and biochemical and pharmacological assays.
Associated faculty- Techniques and strategies for teaching biochemistry, immunology, and molecular biology in higher and basic education
- Development of educational materials in biochemistry, immunology, and molecular biology for use in higher and basic education.
- Techniques and strategies for scientific communication.
Associated faculty- Stem cell biology for biotechnological applications.
Associated faculty- Genomics and functional genomics: genome and transcriptome sequencing and analysis, genome editing (CRISPR-Cas9)
- Gene expression regulation
- DNA repair mechanisms
- Sequencing and functional analysis of small non-coding RNAs (e.g., microRNAs, siRNAs, piRNAs).
- Evolution of regulatory pathways underlying biological phenomena.
Associated faculty- Purification, cloning, expression, and biological characterization of antigens for recombinant, DNA, and RNA vaccines and diagnostic tests, as well as monoclonal antibodies for diagnostic and technological applications
- Determination of antigen-antibody interactions and antibody repertoire in vaccinated, immunized, or infected individuals to understand the humoral immune response and to develop new therapies and diagnostic tools.
